Diagnostic Code 7533 · 38 CFR §4.115b
DC 7533 covers cystic diseases of the kidneys, primarily polycystic kidney disease (PKD) — a condition where numerous fluid-filled cysts develop in the kidneys, gradually replacing normal tissue and destroying kidney function. While often genetic, the condition can be aggravated by service conditions, and acquired cystic kidney disease can develop from toxic exposures or chronic kidney damage. The condition is progressive and may eventually require dialysis or transplant.
| Rating | Criteria |
|---|---|
| 0% | Albumin and casts with history of acute nephritis, OR hypertension non-compensable under DC 7101. |
| 30% | Constant albuminuria with some edema, OR definite decrease in kidney function, OR hypertension at least 10% disabling under DC 7101. |
| 60% | Constant albuminuria with some edema, OR definite decrease in kidney function, OR hypertension at least 40% disabling under DC 7101. |
| 80% | Persistent edema and albuminuria with BUN 40 to 80 mg%, creatinine 4 to 8 mg%, or generalized poor health characterized by lethargy, weakness, anorexia, weight loss, or limitation of exertion. |
| 100% | Requiring regular dialysis, OR precluding more than sedentary activity from one or more of the symptoms in the 80% level. |
Imaging showing the cystic kidneys is essential. Serial kidney function tests (creatinine, GFR) showing progressive decline over time demonstrate the worsening. Genetic testing confirming PKD supports the diagnosis. If claiming aggravation of a genetic condition, evidence of accelerated progression during or after service is needed. Treatment records showing management of complications support the claim.
Genetic conditions are not directly service-caused, but they can be service-connected under the aggravation theory. If military service conditions — physical stress, toxic exposures, dehydration, medications — accelerated the progression of your PKD beyond its natural course, the worsening can be service-connected. You would need medical evidence comparing your progression rate to typical progression.
Yes. Since cystic kidney disease is progressive, your rating should increase as kidney function declines. File for increased rating when your GFR drops significantly. Keep up with regular lab monitoring so you have the documentation to support increase requests.