Diagnostic Code 7716 · 38 CFR §4.117
Aplastic anemia is a condition where the bone marrow fails to produce enough blood cells — red blood cells, white blood cells, and platelets are all reduced. This leads to fatigue and weakness (from anemia), frequent infections (from low white cells), and easy bleeding and bruising (from low platelets). The condition can be life-threatening. For veterans, aplastic anemia can result from toxic chemical exposure during service (benzene, pesticides, herbicides), radiation exposure, or certain medications prescribed during service. It may also be triggered by viral infections acquired during deployment. Treatment ranges from blood transfusions and growth factors to bone marrow transplant in severe cases.
| Rating | Criteria |
|---|---|
| 30% | Aplastic anemia requiring intermittent treatment such as occasional transfusions or growth factor therapy, with moderate symptoms. |
| 60% | Aplastic anemia requiring regular transfusions and/or continuous immunosuppressive therapy, with persistent symptoms despite treatment. |
| 100% | Severe aplastic anemia requiring frequent transfusions, bone marrow transplant, or continuous intensive treatment, with life-threatening complications. |
Complete blood counts showing pancytopenia (low counts across all cell lines) are essential. Bone marrow biopsy confirming the aplastic anemia diagnosis is critical. Hematology treatment records documenting transfusions, medications, and any transplant procedures are needed. Service records or exposure documentation linking the condition to toxic exposure, radiation, or medications during service establish nexus. A hematology nexus opinion is strongly recommended.
Yes. Benzene, certain pesticides, herbicides, and radiation exposure are known causes of aplastic anemia. If you were exposed to these substances during military service, the condition can be service-connected with appropriate documentation and nexus opinion.