Diagnostic Code 7717 · 38 CFR §4.117
AL amyloidosis (primary amyloidosis) is a condition where abnormal proteins (amyloid) produced by the bone marrow deposit in organs and tissues, causing organ damage. It can affect the heart, kidneys, liver, nervous system, and digestive tract. The condition is related to an underlying plasma cell disorder. For veterans, AL amyloidosis is a presumptive condition for Agent Orange exposure. It can also result from other toxic exposures during service. The VA assigns a mandatory 100 percent rating during active disease, with reassessment based on residual organ damage after treatment.
| Rating | Criteria |
|---|---|
| 100% | Active AL amyloidosis or during treatment. After treatment, residual organ damage (heart, kidneys, nerves, etc.) is rated under the applicable organ system diagnostic codes. |
Tissue biopsy confirming amyloid deposits is the definitive diagnostic evidence. Hematology records documenting the underlying plasma cell disorder are needed. Records of organ involvement (cardiac echo, kidney function tests, nerve conduction studies) demonstrate the extent of disease. For Agent Orange claims, proof of qualifying service is sufficient for nexus. For other claims, an oncology or hematology nexus opinion is needed.
Yes. AL amyloidosis is on the Agent Orange presumptive list. Veterans who served in qualifying locations need only show proof of service and the diagnosis.